![]() A retrospective analysis was performed identifying children with Pierre Robin sequence and Treacher Collins syndrome undergoing computed tomography. The purpose of this study was to therefore compare mandibular morphology in children with Pierre Robin sequence with children with Treacher Collins syndrome using three-dimensional analysis of computed tomographic scans. It has been hypothesized, however, that the mandible may be differentially affected. These findings underscore distinct considerations that must be made in surgical planning for reconstruction.Ībstract = "Pierre Robin sequence and Treacher Collins syndrome are both associated with mandibular hypoplasia. Three-dimensional mandibular morphometric analysis in patients with Pierre Robin sequence and Treacher Collins syndrome thus revealed distinctly different patterns of mandibular hypoplasiarelative to normal controls. In addition, the gonial angle was more obtuse in both the Pierre Robin sequence and Treacher Collins syndrome groups compared with the controls. ![]() This resulted in distinctly different ramus height-mandibular body length ratios. Mandibular body length was found to be significantly shorter for children with Pierre Robin sequence, whereas ramus height was significantly shorter for children with Treacher Collins syndrome. These were then compared with those in control children with normal mandibles and with the clinical norms corrected for age and sex based on previously published measurements. Three-dimensional reconstruction was performed, and ramus height, mandibular body length, and gonial angle were measured. ![]() Pierre Robin sequence and Treacher Collins syndrome are both associated with mandibular hypoplasia. ![]()
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